A study testing whether metformin from AgelessRx, a long-used diabetes pill, affects healthy aging.
What this means for you
- Who can join
- Adults 40 to 85, are joining a healthy-aging study, BMI 22+.
- What you take
- Metformin, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
- How long it lasts
- The study runs about 8 months.
- What you get
- The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
What this study is for
Primary condition: Longevity. Also studied in: GLP-1, Geroscience, Aging.
Full scientific study title: Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation.
Who can join
Adults 40 to 85, are joining a healthy-aging study, BMI 22+. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.
Full medical eligibility (for you and your doctor)verbatim from the registry
This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.
Key inclusion criteria
- Existing AgelessRx patient
- Adults (40 - 85 years of age)
- Any sex
- Any ethnicity
- BMI >= 22 kg/m^2
Key exclusion criteria
- Individuals who are denied a longevity product by the AgelessRx medical team will not be asked to participate in any product specific test(s) or questionnaire(s)
- History of bariatric surgery
- Use of weight-loss medications other than GLP-1s within the past 6 months
- Age <40 years
- Contraindications to naltrexone, metformin, or rapamycin
Where this study is enrolling
This trial has 1 sites across 1 state. Contact a site coordinator directly to start screening.
Illinois1 site
- AgelessRxChicago, Illinois
Timeline
Started enrolling: 2024-12-17. Expected completion: 2025-08. Last updated on ClinicalTrials.gov: 2025-07-30.
Official source
We sync this data quarterly from ClinicalTrials.gov, the federal registry for clinical research. Before contacting a site, verify the trial is still recruiting on the official page:
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