A study testing whether a new weekly shot from University of Virginia, tirzepatide, can help with weight.
What this means for you
- Who can join
- Adults 30 to 65, have obesity or are overweight, BMI 27+.
- What you take
- tirzepatide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
- How long it lasts
- The study runs about 10 months.
- What you get
- The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
What this study is for
Primary condition: Obesity & Overweight.
Full scientific study title: The Effect of Exercise and Tirzepatide on Weight and Health Outcomes (EXER-MED).
Who can join
Adults 30 to 65, have obesity or are overweight, BMI 27+. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.
Full medical eligibility (for you and your doctor)verbatim from the registry
This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.
Key inclusion criteria
- Men and women 30-65 years of age, postmenopausal women included
- 27-29.9 with an additional CVD risk factor or 30-40 kg/m2
- For overweight adults only: additional cardiometabolic risk factor (diagnosed dyslipidemia, hypertension)
- Willingness and adequate health to go on weight loss medication
- The capability and willingness to provide written informed consent
Key exclusion criteria
- Including but not limited to serious arrhythmias
- Cardiomyopathy
- Congestive heart failure
- Stroke or transient ischemic attacks
- Peripheral vascular disease
Where this study is enrolling
This trial has 1 sites across 1 state. Contact a site coordinator directly to start screening.
Virginia1 site
- University of VirginiaCharlottesville, VirginiaDamon L Swift, Ph.D.(434) 924-1436
Timeline
Started enrolling: 2026-08. Expected completion: 2027-06. Last updated on ClinicalTrials.gov: 2026-05-06.
Official source
We sync this data quarterly from ClinicalTrials.gov, the federal registry for clinical research. Before contacting a site, verify the trial is still recruiting on the official page:
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