A study testing whether a GLP-1 medicine from Emory University, semaglutide, can lower blood sugar and help with weight.
What this means for you
- Who can join
- Adults 65+, women only, have type 2 diabetes, BMI 27+.
- What you take
- semaglutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
- How long it lasts
- The full study runs about 2.6 years; your own time in it is usually shorter.
- What you get
- The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
What this study is for
Primary condition: Diabetes Mellitus, Type 2.
Full scientific study title: Investigating the Impact of GLP-1 RA Therapy on Osteosarcopenia in Older Female Adults With Diabetes.
Who can join
Adults 65+, women only, have type 2 diabetes, BMI 27+. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.
Full medical eligibility (for you and your doctor)verbatim from the registry
This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.
Key inclusion criteria
- Postmenopausal women aged 65 years or older
- Has type 2 diabetes
- Body Mass Index (BMI) >=27 kg/m² to max 40kg/m2 (inclusive)
- Hemoglobin A1c between 7-10% within 3 months of the first visit.
- Willingness and ability to comply with all study procedures, including fasting requirements for certain visits.
Key exclusion criteria
- Patients with type 1 diabetes mellitus or other types of diabetes that are not T2D
- eGFR <30 ml/min in the last 3 months
- Patients with a history of treatment with anti-osteoporosis agents
- Documented primary or secondary osteoporosis on a DEXA scan within the last 12 months, or are on osteoporosis therapies
- Documented presence of prosthesis or devices in the spine or hip
Where this study is enrolling
This trial has 1 sites across 1 state. Contact a site coordinator directly to start screening.
Georgia1 site
- Grady Memorial HospitalAtlanta, Georgia
Timeline
Started enrolling: 2026-04. Expected completion: 2028-11. Last updated on ClinicalTrials.gov: 2026-02-24.
Official source
We sync this data quarterly from ClinicalTrials.gov, the federal registry for clinical research. Before contacting a site, verify the trial is still recruiting on the official page:
Other GLP-1 clinical trials
Back to the full directory → or take the matching quiz if you want clinical trials filtered to your conditions and location.
