A study testing whether a new weekly shot from The University of Texas Health Science Center at San Antonio, tirzepatide, can lower blood sugar and help with weight.
What this means for you
- Who can join
- Adults 18 to 75, have type 2 diabetes.
- What you take
- tirzepatide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
- How long it lasts
- The full study runs about 4.6 years; your own time in it is usually shorter.
- What you get
- The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
What this study is for
Primary condition: Type 2 Diabetes (Adult Onset).
Full scientific study title: Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes.
Who can join
Adults 18 to 75, have type 2 diabetes. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.
Full medical eligibility (for you and your doctor)verbatim from the registry
This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.
Key inclusion criteria
- Ability of subject to understand and the willingness to sign a written informed consent document.
- Males and females; Age 18-75 years
- Recently (within 5 years) diagnosed Type 2 Diabetes Mellitus (T2DM) patients
- Drug naïve or receiving metformin monotherapy
- HbA1c >6.5% (no limit on upper HbA1c value);
Key exclusion criteria
- positive anti-GAD (antibodies to glutamic acid decarboxylase)
- pregnancy or plan of becoming pregnant
- evidence of proliferative diabetic retinopathy,
- plasma creatinine >1.4 females or >1.5 males;
- presence of congestive heart failure (CHF);
Where this study is enrolling
This trial has 2 sites across 1 state. Contact a site coordinator directly to start screening.
Texas2 sites
- University Health System Texas Diabetic InstituteSan Antonio, Texas
- UT Health Science CenterSan Antonio, Texas
Timeline
Started enrolling: 2024-11-07. Expected completion: 2029-06-30. Last updated on ClinicalTrials.gov: 2026-03-10.
Official source
We sync this data quarterly from ClinicalTrials.gov, the federal registry for clinical research. Before contacting a site, verify the trial is still recruiting on the official page:
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