Home›Clinical trials›A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
Enrolling now · NCT07253285

A study testing whether a study medicine from Novo Nordisk, cagrilintide, can help with weight.

What this means for you

Who can join
Children and teens 8 to 18, are overweight.
What you take
cagrilintide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
How long it lasts
The full study runs about 7.7 years; your own time in it is usually shorter.
What you get
The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
Phase Phase 3Sponsor Novo Nordisk A/SDrug cagrilintideClass OtherSites 34 USEnrollment target 460

What this study is for

Primary condition: Overweight. Also studied in: Obesity.

Full scientific study title: A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight.

Who can join

Age8 to 18SexAny

Children and teens 8 to 18, are overweight. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.

Full medical eligibility (for you and your doctor)verbatim from the registry

This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.

Key inclusion criteria

  • Informed consent of parent(s) or legally acceptable representative (LAR) of participant and child assent, as age-appropriate, obtained before any study related activities. Study related activities are any procedures that are carried out as part of the study, including activities to determine suitability for the study.
  • The parent(s) or LAR of the child must sign and date the Informed Consent Form (according to local requirements)
  • The child must sign and date the Child Assent Form or provide oral assent (according to local requirements).
  • Male or female.
  • Aged 8 to less than (<) 18 years at the time of signing the informed consent.

Key exclusion criteria

  • Treatment with any medication prescribed for obesity or weight management within 90 days before screening.
  • Previous or planned (during the study period) obesity treatment with surgery or a weight loss device. However, the following are allowed:
  • Liposuction and/or abdominoplasty, if performed > 1 year before screening.
  • Adjustable gastric banding, if the band has been removed > 1 year before screening.
  • Intragastric balloon, if the balloon has been removed > 1 year before screening.

Where this study is enrolling

This trial has 34 sites across 19 states. Contact a site coordinator directly to start screening.

California1 site
  • Neighborhood Healthcare
    Escondido, California
Florida3 sites
  • Encore Medical Research LLC
    Hollywood, Florida
  • Jacksonville Ctr for Clin Res
    Jacksonville, Florida
  • Encore Medical Research of Weston
    Weston, Florida
Georgia4 sites
  • Children's Healthcare Atlanta
    Atlanta, Georgia
  • Columbus Research Foundation
    Columbus, Georgia
  • Accel Research Sites-NeuroStudies
    Decatur, Georgia
  • Eastside Bariatric and Gen Surg
    Snellville, Georgia
Idaho1 site
  • Solaris Clinical Research
    Meridian, Idaho
Indiana1 site
  • IU Health - Riley Physicians Endo-Diab
    Indianapolis, Indiana
Kansas1 site
  • Cotton O'Neil Clinical Research Center
    Topeka, Kansas
Louisiana1 site
  • Pennington Biomed Res Ctr
    Baton Rouge, Louisiana
Maryland1 site
  • Barry J. Reiner, MD LLC
    Baltimore, Maryland
Minnesota2 sites
  • University of Minnesota
    Minneapolis, Minnesota
  • AES Minneapolis DRS
    Richfield, Minnesota
New York3 sites
  • UBMD Physicians Group - Pediatrics - Conventus
    Buffalo, New York
  • SUNY Upstate Medical Univ - Syracuse
    Syracuse, New York
  • Advantage Clinical Trials
    The Bronx, New York
North Dakota1 site
  • Valley Weight Loss Clinic
    Fargo, North Dakota
Ohio2 sites
  • Centricity Research - Ohio
    Columbus, Ohio
  • PriMed Clinical Research
    Dayton, Ohio
Oklahoma1 site
  • Children's Physicians OU
    Oklahoma City, Oklahoma
Pennsylvania1 site
  • UPMC Child Hosp-Pittsburgh
    Pittsburgh, Pennsylvania
South Carolina2 sites
  • Prisma Health-Ped Endo
    Greenville, South Carolina
  • Coastal Carolina Research Ctr
    North Charleston, South Carolina
South Dakota1 site
  • Monument Health Clinical Rsrch
    Rapid City, South Dakota
Tennessee1 site
  • LifeDoc Health
    Memphis, Tennessee
Texas6 sites
  • DM Clinical
    Houston, Texas
  • DM Clinical
    San Antonio, Texas
  • The Texas Liver Institute
    San Antonio, Texas
  • Pinnacle Clinical Research
    San Antonio, Texas
  • Consano Clin Res-Shavano Park
    Shavano Park, Texas
  • Texas Valley Clinical Research
    Weslaco, Texas
Utah1 site
  • Wee Care Pediatrics
    Syracuse, Utah

Timeline

Started enrolling: 2026-01-08. Expected completion: 2033-09-20. Last updated on ClinicalTrials.gov: 2026-04-02.

Official source

We sync this data quarterly from ClinicalTrials.gov, the federal registry for clinical research. Before contacting a site, verify the trial is still recruiting on the official page:

View on ClinicalTrials.gov →

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